MAFI

Mechanistic intelligence for pharmaceutical and biotechnology decision-making

MAFI decomposes a therapeutic programme into its mechanistic dependencies, assesses each for fragility, and benchmarks them against comparable programmes.

300+

Drug Programmes

2400+

Mechanistic Dependencies

5

Fragility Domains

MAFI evaluates drug-development programmes using a purpose-built historical database of 300+ programmes and 2,400+ mechanistic dependencies, assessed across five fragility domains.

From proprietary intelligence to programme-level insight.

MAFI translates its structured database and assessment framework into two complementary analytical products.

  • MBR

    (Mechanistic Benchmarking Report)

    Compares the programme’s mechanistic architecture, domain-level assessments and overall fragility profile against relevant historical comparators.

    Read more about the MBR

  • MDDR

    (Mechanistic Due Diligence Report)

    Assesses a programme’s mechanism of action in absolute terms - what it depends on, how fragile those dependencies are, and where failure would originate.

    Read more about the MDDR
Read more about MAFI Assessments

Initiate an Assessment

Enquire about a MAFI assessment here.

Have a question?

contact us at contact@mafi-intelligence.com